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Indibulin

Catalog No.: A21210

Tubulin assembly inhibitor

Indibulin

Indibulin Chemical Structure

CAS NO. 204205-90-3

Indibulin (ZIO 301), an orally applicable inhibitor of tubulin assembly, shows potent anticancer activity with a minimal neurotoxicity.

Availability: In stock

Package Price Qty
5 mg
$99.00
10 mg
$171.00
50 mg
$506.00
100 mg
$1,012.00
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Biological Activity

Indibulin (ZIO 301), an orally applicable inhibitor of tubulin assembly, shows potent anticancer activity with a minimal neurotoxicity.
In vitro DMSO 37 mg/mL (94.91 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.65 mL 128.26 mL 256.52 mL
0.5 mM 5.13 mL 25.65 mL 51.3 mL
1 mM 2.57 mL 12.83 mL 25.65 mL
5 mM 0.51 mL 2.57 mL 5.13 mL

*The above data is based on the productmolecular weight 389.83. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21210
Actions Inhibitor
CAS No. 204205-90-3
Formula C22H16ClN3O2
M. Wt 389.83
Purity >98%
Synonyms ZIO 301, ZIO301, ZIO-301; D 24851, D24851, D-24851
SMILES O=C(NC1=CC=NC=C1)C(C2=CN(CC3=CC=C(Cl)C=C3)C4=C2C=CC=C4)=O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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