Biological Activity
Indirubin-3'-monoxime is a powerful inhibitor of GSK-3β with IC50 of 22nM, also inhibits CDK1/5 (IC50 = 180/100 nM).
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 36.06 mL | 180.32 mL | 360.65 mL |
0.5 mM | 7.21 mL | 36.06 mL | 72.13 mL |
1 mM | 3.61 mL | 18.03 mL | 36.06 mL |
5 mM | 0.72 mL | 3.61 mL | 7.21 mL |
*The above data is based on the productmolecular weight 277.28. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A16280 |
---|---|
Actions | Inhibitor |
M. Wt | 277.28 |
Formula | C16H11N3O2 |
Solubility | DMSO |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 160807-49-8 |
SMILES | O=C1N=C2C(C=CC=C2)=C1C(NC3=CC=CC=C43)=C4NO |
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