Indirubin-3-monoxime

Catalog No.: A16280

GSK-3β inhibitor

Indirubin-3-monoxime

Indirubin-3-monoxime Chemical Structure

CAS NO. 160807-49-8

Indirubin-3'-monoxime is a powerful inhibitor of GSK-3β with IC50 of 22nM, also inhibits CDK1/5 (IC50 = 180/100 nM).

Availability: In stock

Package Price Qty
5 mg
$60.00
10 mg
$100.00
50 mg
$400.00
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Biological Activity

Indirubin-3'-monoxime is a powerful inhibitor of GSK-3β with IC50 of 22nM, also inhibits CDK1/5 (IC50 = 180/100 nM).
In vitro DMSO 53 mg/mL (191.14 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 36.06 mL 180.32 mL 360.65 mL
0.5 mM 7.21 mL 36.06 mL 72.13 mL
1 mM 3.61 mL 18.03 mL 36.06 mL
5 mM 0.72 mL 3.61 mL 7.21 mL

*The above data is based on the productmolecular weight 277.28. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16280
Actions Inhibitor
CAS No. 160807-49-8
Formula C16H11N3O2
M. Wt 277.28
Purity >98%
SMILES O=C1N=C2C(C=CC=C2)=C1C(NC3=CC=CC=C43)=C4NO
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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