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- Jingjing Ding, .et al. Self-Activatable Photo-Extracellular Vesicle for Synergistic Trimodal Anticancer Therapy, Adv Mater, 2021, Feb;33(7):e2005562 PMID: 33432702
- Dos Santos Câmara AL, .et al. Acid-sensitive lipidated doxorubicin prodrug entrapped in nanoemulsion impairs lung tumor metastasis in a breast cancer model, Nanomedicine (Lond), 2017, Aug;12(15):1751-1765 PMID: 28703043
Biological Activity
Aldoxorubicin, also known as INNO-206, is the 6-maleimidocaproyl hydrazone derivative prodrug of the anthracycline antibiotic doxorubicin (DOXO-EMCH) with antineoplastic activity.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 13.32 mL | 66.6 mL | 133.2 mL |
| 0.5 mM | 2.66 mL | 13.32 mL | 26.64 mL |
| 1 mM | 1.33 mL | 6.66 mL | 13.32 mL |
| 5 mM | 0.27 mL | 1.33 mL | 2.66 mL |
*The above data is based on the productmolecular weight 750.75. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A12326 |
|---|---|
| CAS No. | 151038-96-9 |
| Formula | C37H42N4O13 |
| M. Wt | 750.75 |
| Purity | >98% |
| SMILES | C[[email protected]]1[[email protected]]([[email protected]](C[[email protected]@H](O1)O[[email protected]]2C[[email protected]@](CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(/C(=N\NC(=O)CCCCCN6C(=O)C=CC6=O)/CO)O)N)O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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