Intoplicine dimesylate

Catalog No.: A57194
Topoisomerase I/II Inhibitor
Intoplicine dimesylate is a potent inhibitor of DNA topoisomerase I and II. This compound, a derivative of the 7H-benzo[e]pyrido[4,3-b]indole series, exerts its antitumor effects by strongly binding to DNA, resulting in an increased length of linear DNA. Intoplicine dimesylate is useful in cancer research and studies involving DNA topology.
Grouped product items
Size Price Stock Qty
5mg
$510.00
In stock
10mg
$855.00
In stock
25mg
$1,720.00
In stock
50mg
$2,705.00
In stock
100mg
$4,240.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionIntoplicine dimesylate is a potent inhibitor of DNA topoisomerase I and II. This compound, a derivative of the 7H-benzo[e]pyrido[4,3-b]indole series, exerts its antitumor effects by strongly binding to DNA, resulting in an increased length of linear DNA. Intoplicine dimesylate is useful in cancer research and studies involving DNA topology.
Product Information
Catalog NumA57194
FormulaC23H32N4O7S2
Molecular Weight540.65
CAS Number133711-99-6
SMILESOC1=CC=C2C3=C(NC4=C3C(NCCCN(C)C)=NC=C4C)C=CC2=C1.CS(O)(=O)=O.CS(O)(=O)=O
SynonymsRP 60475 dimesylate
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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