Iodo-PEG3-N3 is a PEG-based PROTAC linker designed for synthesizing Proteolysis Targeting Chimeras (PROTACs). This compound features an azide group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, Iodo-PEG3-N3 can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN functionalized molecules, making it highly versatile for chemical biology applications in targeted protein degradation research.
Iodo-PEG3-N3 is a PEG-based PROTAC linker designed for synthesizing Proteolysis Targeting Chimeras (PROTACs). This compound features an azide group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, Iodo-PEG3-N3 can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN functionalized molecules, making it highly versatile for chemical biology applications in targeted protein degradation research.
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