IPI-145 (Duvelisib, INK1197)

Catalog No.: A12422
PI3K-δ/PI3K-γ inhibitor
IPI-145, also known as INK-1197, is an orally bioavailable, highly selective and potent small molecule inhibitor of the delta and gamma isoforms of phosphoinositide-3 kinase (PI3K) with potential immunomodulating and antineoplastic activities.
Grouped product items
Size Price Stock Qty
2mg
$35.00
In stock
5mg
$55.00
In stock
10mg
$80.00
In stock
25mg
$125.00
In stock
50mg
$150.00
In stock
100mg
$250.00
In stock
10mM * 1mL in DMSO
$85.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Biological Activity
Discription IPI-145, also known as INK-1197, is an orally bioavailable, highly selective and potent small molecule inhibitor of the delta and gamma isoforms of phosphoinositide-3 kinase (PI3K) with potential immunomodulating and antineoplastic activities.
Targets
Target Value
Cell Research
Cell Line Type Value Description References
Product Information
Catalog Num A12422
Formula C22H17ClN6O
Molecular Weight 416.86
CAS Number 1201438-56-3
SMILES C[C@@H](C1=CC2=C(C(=CC=C2)Cl)C(=O)N1C3=CC=CC=C3)NC4=NC=NC5=C4NC=N5
Synonyms IPI145; IPI 145; IPI-145. INK-1197; INK 1197; INK1197
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 76 mg/mL (182.31 mM)
Water Insoluble
Ethanol Insoluble
In vivo 30% PEG400+0.5% Tween80+5% propylene glycol 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.99 mL 119.94 mL 239.89 mL
0.5 mM 4.8 mL 23.99 mL 47.98 mL
1 mM 2.4 mL 11.99 mL 23.99 mL
5 mM 0.48 mL 2.4 mL 4.8 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

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Please check COA/MSDS for correct molecular weight.

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