Eganelisib (IPI-549)
Catalog No.: A16332
PI3Kγ Inhibitor
IPI-549 is a potent and selective PI3Kγ Inhibitor with IC50 of 16 nM.
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Biological Activity
| Description | IPI-549 is a potent and selective PI3Kγ Inhibitor with IC50 of 16 nM. | |||||
|---|---|---|---|---|---|---|
| Targets |
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| Cell Research |
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Product Information
| Catalog Num | A16332 |
|---|---|
| Formula | C30H24N8O2 |
| Molecular Weight | 528.56 |
| CAS Number | 1693758-51-8 |
| SMILES | O=C1N(C2=CC=CC=C2)C([C@@H](NC(C3=C(N=CC=C4)N4N=C3N)=O)C)=CC5=CC=CC(C#CC6=CN(C)N=C6)=C51 |
| Synonyms | IPI549, IPI 549 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Solubility
| In vitro | DMSO | 87 mg/mL (164.6 mM) | |
| Water | Insoluble | ||
| Ethanol | 7 mg/mL (13.24 mM) | ||
| * <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. | |||
Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.92 mL | 94.6 mL | 189.19 mL |
| 0.5 mM | 3.78 mL | 18.92 mL | 37.84 mL |
| 1 mM | 1.89 mL | 9.46 mL | 18.92 mL |
| 5 mM | 0.38 mL | 1.89 mL | 3.78 mL |
Useful Calculator
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)
Please check COA/MSDS for correct molecular weight.
Calculate the dilution required to prepare a stock solution.This equation is commonly abbreviated as: C1V1 = C2V2
