Catalog No.: A16332

PI3Kγ Inhibitor


IPI-549 Chemical Structure

CAS NO. 1693758-51-8

IPI-549 is a potent and selective PI3Kγ Inhibitor with IC50 of 16 nM.

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Biological Activity

IPI-549 is a potent and selective PI3Kγ Inhibitor with IC50 of 16 nM.
In vitro DMSO 87 mg/mL (164.6 mM)
Water Insoluble
Ethanol 7 mg/mL (13.24 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.92 mL 94.6 mL 189.19 mL
0.5 mM 3.78 mL 18.92 mL 37.84 mL
1 mM 1.89 mL 9.46 mL 18.92 mL
5 mM 0.38 mL 1.89 mL 3.78 mL

*The above data is based on the productmolecular weight 528.56. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16332
Actions Inhibitor
CAS No. 1693758-51-8
Formula C30H24N8O2
M. Wt 528.56
Purity >98%
Synonyms IPI549, IPI 549
SMILES O=C1N(C2=CC=CC=C2)C([[email protected]@H](NC(C3=C(N=CC=C4)N4N=C3N)=O)C)=CC5=CC=CC(C#CC6=CN(C)N=C6)=C51

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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