Irbesartan (Avapro)

Catalog No.: A10477

AT1 antagonist

Irbesartan (Avapro)

Irbesartan (Avapro) Chemical Structure

CAS NO. 138402-11-6

Irbesartan is an angiotensin II receptor antagonist used mainly for the treatment of hypertension.

Availability: In stock

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10 mg
$45.00
50 mg
$95.00
100 mg
$160.00
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Biological Activity

Irbesartan is an angiotensin II receptor antagonist used mainly for the treatment of hypertension.
Targets
AT1 receptor
1.3 nM
In vitro (25°C) DMSO Warmed: 3 mg/mL (7 mM)
Water Insoluble
Ethanol 3 mg/mL (7 mM)
In vivo 30% PEG400+0.5% Tween80+5% propylene glycol 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.34 mL 116.69 mL 233.37 mL
0.5 mM 4.67 mL 23.34 mL 46.67 mL
1 mM 2.33 mL 11.67 mL 23.34 mL
5 mM 0.47 mL 2.33 mL 4.67 mL

*The above data is based on the productmolecular weight 428.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10477
Actions Antagonist
CAS No. 138402-11-6
Formula C25H28N6O
M. Wt 428.5
Solubility DMSO
Purity >98%
Synonyms BMS-186295, SR-47436, Aprovel, Karvea, BMS186295
SMILES CCCCC1=NC2(CCCC2)C(=O)N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NNN=N5
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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