Isbogrel

Catalog No.: A63259
TXA2 Inhibitor
Isbogrel is a selective inhibitor of thromboxane A2 (TXA2) synthase, demonstrating potent activity in reducing TXA2 generation in the bloodstream. With an ID50 value of 0.04 mg/kg, Isbogrel exhibits effective oral bioavailability. This compound is primarily utilized in research focused on cardiovascular diseases and thrombotic disorders, contributing to the understanding of TXA2's role in platelet aggregation and vascular functions.
Grouped product items
Size Price Stock Qty
1mg
$170.00
In stock
5mg
$410.00
In stock
10mg
$570.00
In stock
25mg
$800.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionIsbogrel is a selective inhibitor of thromboxane A2 (TXA2) synthase, demonstrating potent activity in reducing TXA2 generation in the bloodstream. With an ID50 value of 0.04 mg/kg, Isbogrel exhibits effective oral bioavailability. This compound is primarily utilized in research focused on cardiovascular diseases and thrombotic disorders, contributing to the understanding of TXA2's role in platelet aggregation and vascular functions.
Product Information
Catalog NumA63259
FormulaC18H19NO2
Molecular Weight281.35
CAS Number89667-40-3
SMILESOC(CCCC/C=C(C1=CN=CC=C1)\C2=CC=CC=C2)=O
SynonymsCV-4151
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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