Isotope-Labeled Compounds

20:0-20:1-20:0 TG-d5 is a deuterium-labeled triglyceride used as a stable isotope in lipid metabolism studies. This compound serves as a valuable tracer in metabolic and pharmacokinetic research, allowing for the investigation of lipid dynamics in biological systems. Its stable isotope labeling enhances the sensitivity and accuracy of analytical techniques such as mass spectrometry, facilitating detailed studies of lipid transport and accumulation in various tissues.

Octocrylene-d10 is a deuterium-labeled derivative of octocrylene, an organic ultraviolet (UV) filter primarily targeting UVB radiation and short-wave UVA. This stable isotope is valuable in chemical and biological research for studying the photostability and degradation of UV filters, as well as their environmental impact. Applications include tracking the fate of UV filters in biological systems and assessing their interactions with various matrices.

Guanosine-13C5 is a stable isotope-labeled derivative of guanosine. This deuterated compound serves as a tracer in metabolic studies and is valuable for applications in nucleic acid research. By enhancing the detection and quantification of guanosine in biological systems, Guanosine-13C5 facilitates investigations into nucleotide metabolism and cellular processes involving RNA.

(Rac)-Ruxolitinib-d8 is a stable isotope-labeled derivative of (Rac)-Ruxolitinib, which primarily acts as a Janus kinase (JAK) inhibitor. This compound is utilized in research applications for the quantification and tracking of drug metabolism, pharmacokinetics, and pharmacodynamics in biological systems. The deuterated form enhances analytical measurement accuracy, making it a valuable tool in pharmacological studies.

Bromocyclohexane-d11 is a stable isotope-labeled compound primarily used in isotope labeling applications. This deuterated form of bromocyclohexane serves as an essential tool in NMR studies and mechanistic investigations in organic synthesis. Researchers utilize Bromocyclohexane-d11 to trace and quantify reaction pathways, enhancing the understanding of chemical processes and interactions in various biological systems.

C18 Dihydroceramide-d3 is a deuterium-labeled derivative of C18 Dihydroceramide, serving as a stable isotope standard in biochemical research. This compound is integral for studying sphingolipid metabolism and dynamics, as well as in the analysis of lipid profiles in biological samples. Its application extends to cell biology and metabolic studies, facilitating insights into cellular signaling and membrane structure.

Barnidipine-d5 is a deuterium-labeled analog of Barnidipine, functioning as an L-type calcium antagonist with a strong affinity for [3H] initrendipine binding sites (Ki = 0.21 nmol/l). This compound exhibits selective action on calcium antagonist receptors and serves as an effective antihypertensive agent, primarily reducing peripheral vascular resistance through its vasodilatory effects. Barnidipine-d5 is suitable for research applications focused on cardiovascular pharmacology and calcium channel modulation.

Sodium trifluoroacetate-13C2 is a stable isotope of sodium trifluoroacetate, featuring two carbon-13 atoms. This reagent is widely utilized in isotopic labeling studies, aiding in the tracking of metabolic pathways and the investigation of biochemical interactions. Its unique stable isotope composition makes it an essential tool for applications in NMR spectroscopy and mass spectrometry in chemical and biological research.

Azepan-2-one-d10 is a deuterium-labeled derivative of Azepan-2-one, serving as a stable isotope for various biochemical applications. This compound is utilized in metabolic studies and tracer experiments, allowing for the elucidation of metabolic pathways and the investigation of biological processes. Its labeling with deuterium enhances the sensitivity and accuracy of analytical methods such as NMR and mass spectrometry.

2-Methylpyrazine-d6 is the deuterium-labeled derivative of 2-Methylpyrazine, an alkylpyrazine that occurs naturally in roasted red pepper seed oils. As a stable isotope, it is instrumental in various applications, including isotopic labeling studies and metabolomics research. This reagent facilitates the precise tracing of metabolic pathways and the identification of small molecules in complex biological samples, enhancing the accuracy of analytical techniques.

18:1 SM (d18:1/18:1)-d9 is a deuterated form of sphingomyelin, specifically designed for stable isotope applications. This reagent is utilized in metabolic studies and lipid profiling, allowing for precise quantification and tracking of sphingolipid metabolism in various biological systems. Its stable isotopic labeling makes it suitable for experiments requiring mass spectrometry analysis and helps elucidate the role of sphingomyelin in cellular processes and disease mechanisms.

Mono-Cyclohexyl Phthalate-3,4,5,6-d4 is a stable isotope-labeled compound derived from Mono-Cyclohexyl Phthalate. This deuterium-labeled reagent is essential for applications in metabolic studies and tracer experiments, enabling precise tracking of metabolic pathways and compound metabolism. Its use is integral in environmental analysis and investigations into phthalate behavior in biological systems.

13,14-Dihydro-15-keto-PGE2-d9 is a deuterium-labeled analog of the bioactive lipid prostaglandin E2. This stable isotope is primarily utilized in quantitative mass spectrometry applications for the detailed analysis of prostaglandin metabolism and signaling pathways. It provides a reliable internal standard for the assessment of endogenous levels of 13,14-Dihydro-15-keto-PGE2 in biological samples, aiding in studies related to inflammation, pain, and various physiological processes.

Propofol-d17 β-D-glucuronide is a deuterium-labeled derivative of Propofol β-D-glucuronide, serving as a stable isotope for advanced analytical applications. This compound is widely utilized in pharmacokinetic studies and metabolite profiling to investigate the biotransformation of Propofol in biological systems. Its stable isotopic composition allows for precise quantification and tracking in experimental settings, contributing valuable insights into drug metabolism and safety studies.

DMPG-d54 sodium is a deuterium-labeled derivative of 1,2-Dimyristoyl-sn-glycero-3-phospho-(1'-rac-glycerol). This stable isotope allows for enhanced specificity in membrane biophysics and lipid metabolism studies. It is particularly useful in tracing metabolic pathways and investigating lipid interactions in biological systems. Researchers can utilize DMPG-d54 sodium to gain insights into the dynamics of membrane-associated processes.

Ethane-1,2-diamine-d4 dihydrochloride is a deuterium-labeled derivative of ethane-1,2-diamine, serving as a stable isotope. This compound is commonly used in labeling experiments, aiding in the study of reaction mechanisms and molecular interactions in biological systems. Its unique isotopic signature enhances the sensitivity and specificity of analytical techniques, making it valuable for various research applications in chemical biology and analytical chemistry.

Hexatriacontane-d74 is a deuterium-labeled version of hexatriacontane, serving as a stable isotope for research applications. It facilitates quantitative studies in mass spectrometry and tracer experiments, enabling precise tracking of lipid metabolism and environmental analysis. This compound is valuable for researchers investigating long-chain alkanes and their interactions in various biological systems.

Cetrimonium-d33 bromide is a deuterium-labeled derivative of Cetrimonium bromide, a cationic surfactant with quaternary amine characteristics. This stable isotope is utilized in various research applications, including studies on surfactant behavior, formulation chemistry, and antimicrobial properties. Cetrimonium bromide is also a key component in topical antiseptics, making Cetrimonium-d33 bromide valuable for investigating its interactions and mechanisms in biological systems.

Boc-L-Valine-d8 is a deuterium-labeled derivative of Boc-L-Valine, primarily used as a stable isotope for biochemical research. This reagent serves as an important tool for tracing pathways in metabolic studies and analyzing protein structure through NMR spectroscopy. Its incorporation into biological systems allows for precise quantification and dynamics monitoring in various research applications.

2-Methylimidazole-d6 is a deuterium-labeled derivative of 2-Methylimidazole, serving as a stable isotope for various chemical research applications. This compound is commonly utilized in NMR spectroscopy and mass spectrometry to study metabolic pathways and determine reaction mechanisms. Its isotopic labeling enhances the accuracy of tracking molecular interactions and provides insight into the behavior of imidazole-related compounds in biological systems.

(±)9(10)-DiHOME-d4 is a deuterated derivative of (±)9(10)-DiHOME, featuring stable isotope labeling. This compound is utilized in research to trace and quantify metabolic pathways involving 9(10)-DiHOME, an important lipid mediator implicated in various biological processes. Its stable isotope nature allows for enhanced detection and analysis in biological assays, making it valuable for studies in lipid metabolism and related fields.

Aminoadipic acid-d6 is a stable isotope-labeled form of aminoadipic acid, serving as a valuable tool for metabolic research. As an intermediate in the metabolism of lysine and glycopurine, it aids in the study of amino acid pathways and related biochemical processes. This deuterated compound is essential for applications requiring precise tracking of metabolic flux and analysis in mass spectrometry.

Methyl arachidonate-d8 is a deuterated analog of arachidonic acid methyl ester, serving as a stable isotope. It is utilized in mass spectrometry and isotopic labeling studies to investigate lipid metabolism and signaling pathways. This compound facilitates the accurate quantification of arachidonic acid derivatives in biological samples, enhancing research in pharmacology and biochemistry.

4-Fluorobenzoic acid-13C,d4 is a stable isotope-labeled compound featuring both 13C and deuterium modifications. This reagent serves as a valuable intermediate in the synthesis of various hydrazone derivatives, which exhibit antituberculosis activity, and Schiff bases that demonstrate DPPH radical scavenging properties. Its stable isotopic composition makes it suitable for metabolic and pharmacokinetic studies in chemical research applications.

Sudan III-d6 is a deuterium-labeled derivative of Sudan III, a hydrophobic bisazo dye. The incorporation of stable isotopes allows for enhanced tracking and analysis in biological systems. This reagent is applicable in research involving dye transport, metabolic studies, and stability analysis in various experimental settings. Its unique isotopic labeling provides valuable insights into chemical interactions and behaviors in complex biological matrices.

Fluorene-d10 is a deuterated form of fluorene, a polycyclic aromatic hydrocarbon (PAH) known for its role as a precursor in the synthesis of various fluorene derivatives. This stable isotope is valuable in research applications involving the development of fluorene-based dyes and other advanced materials. Its incorporation enhances the tracking and analysis of molecular behavior in complex systems, making it a crucial tool for studies in organic chemistry and material science.

Digoxigenin-d3 is a deuterium-labeled derivative of Digoxigenin, functioning as a stable isotope. This compound serves as a vital labeling agent in situ hybridization applications, notable for its extended shelf life, rapid detection capabilities, and high sensitivity when used with riboprobes. Digoxigenin-d3 is an essential tool for researchers studying gene expression and molecular interactions.

Indocyanine green-d7 is a deuterium-labeled derivative of the fluorescent dye Indocyanine green. It serves as a stable isotope for tracing applications in medical diagnostics, including the assessment of cardiac output, hepatic function, and liver blood flow dynamics. Additionally, this compound is utilized in ophthalmic angiography, providing valuable insights into vascular health.

Chrysoidine G-d5 hydrochloride is a deuterium-labeled derivative of Chrysoidine G, classified as a stable isotope. This compound serves primarily as a tracer in various chemical research applications, including studies on dye synthesis and textile manufacturing processes. Its concentration can be accurately measured using UV-Vis spectroscopy, making it a valuable tool for analytical and industrial research in dye chemistry.

Pentetic acid-13C5 (Diethylenetriaminepentaacetic acid-13C5) is a stable isotope-labeled derivative of Pentetic acid, recognized for its ability to form robust metal complexes. This compound exhibits significant biological activity in chelating metal ions, which inhibits metal-catalyzed decomposition reactions, particularly in the presence of peroxygen compounds like hydrogen peroxide. Pentetic acid-13C5 is valuable for applications in environmental science, particularly for the removal of heavy metals and dyes from contaminated wastewater through the development of magnetic adsorbents. Its stable carbon isotope labeling allows for advanced tracking and analysis in chemical research studies.

Atazanavir-d9 is a deuterated analog of Atazanavir, a highly selective HIV-1 protease inhibitor. This compound targets the HIV-1 protease enzyme, facilitating the treatment of HIV infections with its ability to inhibit viral replication. Additionally, Atazanavir acts as both a substrate and inhibitor of CYP3A4, as well as an inducer of P-glycoprotein (P-gp). Furthermore, Atazanavir possesses inhibitory activity against SARS-CoV 3CLpro, with an IC50 of 3.49 μM, making it relevant for research in antiviral therapies.

Indene-d3 is a stable isotope-labeled derivative of 1H-Indene, designed for use in various chemical research applications. This compound serves as a valuable internal standard in mass spectrometry and other analytical techniques, enhancing the precision of quantitative analysis. Additionally, Indene-d3 can be utilized in studies involving reaction mechanisms and metabolic pathways, providing insights into the behavior of indene-related compounds in biological systems.

N-Methylpyrrolidone-d3 is a deuterated form of N-Methylpyrrolidone, a polar aprotic solvent widely utilized in chemical synthesis and formulation. This stable isotope serves as a valuable tool in various research applications, including NMR spectroscopy, environmental studies, and metabolic tracing. Its unique properties facilitate enhanced analytical precision in the study of solvent interactions and dynamics in complex mixtures.

Citric acid-d4 trisodium is a deuterium-labeled form of citric acid trisodium, serving as a stable isotope. This compound functions as an acidulant and has been shown to induce apoptosis and promote cell cycle arrest at the G2/M and S phases in HaCaT cells. Additionally, it contributes to oxidative stress in liver cells by reducing the activity of antioxidative enzymes. Citric acid-d4 trisodium is utilized in various research applications, including metabolic studies and the investigation of cellular mechanisms.

N-Myristoylglycine-d2-1 is a deuterium-labeled derivative of N-Myristoylglycine. As a stable isotope, it serves as a crucial tool for metabolic studies and tracer experiments in biological research. This compound aids in elucidating metabolic pathways and assessing the dynamics of fatty acid metabolism in various biological systems. Its unique labeling facilitates precise tracking and quantification in analytical applications.

Modafinil acid sulfone-d5 is a stable isotope-labeled derivative of Modafinil acid sulfone. This compound serves as a valuable tool for metabolic studies and pharmacokinetic research, enabling precise tracing of drug metabolism and distribution in biological systems. Its isotopic labeling enhances the accuracy of analytical methodologies and supports the investigation of Modafinil's biological effects.

1-Decanoyl-2-octanoyl-3-chloropropanediol-13C3 is a stable isotope-labeled derivative of 3-monochloropropanediol (3-MCPD) glycidyl ester. This compound serves as a valuable internal standard for analytical studies involving lipid oxidation and the assessment of food safety. Its use in research facilitates the understanding of metabolic pathways and the quantification of 3-MCPD in complex biological matrices.

1,2-Dilinolenoyl-3-chloropropanediol-d5 is a deuterated derivative of 3-monochloropropanediol (3-MCPD) glycidyl ester. This stable isotope serves as a useful internal standard in mass spectrometry applications, facilitating accurate quantification in various lipid and metabolic studies. Its incorporation into research can aid in the elucidation of metabolic pathways and the analysis of lipid metabolism.

1-Decanoyl-2-lauroyl-3-chloropropanediol-13C3 is a stable isotope-labeled derivative of 3-monochloropropanediol (3-MCPD) glycidyl ester. This compound can be used in various analytical studies focused on lipid metabolism and the assessment of food safety. Its stable isotope labeling facilitates precise quantification and tracking of metabolic pathways in research applications involving chloropropanediol derivatives.

1-Octanoyl-2-decanoyl-3-chloropropanediol-d5 is a deuterated derivative of 3-monochloropropanediol (3-MCPD) glycidyl ester. This stable isotope is utilized in research to investigate the metabolic pathways and toxicological profiles of chloropropanediols. Its unique isotopic labeling allows for enhanced detection and quantification in complex biological samples, making it valuable for studies in food safety and environmental analysis.

rac-1-Lauroyl-2-decanoyl-3-chloropropanediol-d5 is a deuterated derivative of 3-monochloropropanediol (3-MCPD), functioning as a stable isotope tracer. This compound is utilized in chemical research to study metabolic pathways and structural analysis of lipids. Its unique isotopic label assists in enhancing the accuracy of quantitative analysis in complex biological systems.

1-Lauroyl-2-decanoyl-3-chloropropanediol-d5 is a deuterated derivative of 3-monochloropropanediol (3-MCPD) designed for stable isotope labeling applications. This compound can aid in the study of lipid metabolic pathways and the characterization of food-derived glycidyl esters. It is particularly valuable in research involving fatty acid metabolism and the safety assessment of food additives.

Pseudomonas quinolone signal-d4 is a stable isotope internal standard that facilitates the quantitative analysis of Pseudomonas aeruginosa signaling molecules. This compound serves as a valuable tool in research applications focusing on bacterial communication and quorum sensing. Its precise isotopic labeling enhances the accuracy and reliability of analytical techniques such as mass spectrometry.

3-Chloro-2-(octanoyloxy)propyl decanoate-d5 is a stable isotope-labeled glycerolipid that serves as a valuable tool in lipid metabolism studies and tracer experiments. Its stable isotope labeling enables accurate measurement and tracking of lipid components in biological systems. This reagent is suitable for research applications involving metabolic labeling, lipid profiling, and understanding lipid-related diseases.