Barnidipine-d5

Catalog No.: B11945
Stable Isotope
Barnidipine-d5 is a deuterium-labeled analog of Barnidipine, functioning as an L-type calcium antagonist with a strong affinity for [3H] initrendipine binding sites (Ki = 0.21 nmol/l). This compound exhibits selective action on calcium antagonist receptors and serves as an effective antihypertensive agent, primarily reducing peripheral vascular resistance through its vasodilatory effects. Barnidipine-d5 is suitable for research applications focused on cardiovascular pharmacology and calcium channel modulation.
Grouped product items
Size Price Stock Qty
1mg
$385.00
In stock
5mg
$985.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionBarnidipine-d5 is a deuterium-labeled analog of Barnidipine, functioning as an L-type calcium antagonist with a strong affinity for [3H] initrendipine binding sites (Ki = 0.21 nmol/l). This compound exhibits selective action on calcium antagonist receptors and serves as an effective antihypertensive agent, primarily reducing peripheral vascular resistance through its vasodilatory effects. Barnidipine-d5 is suitable for research applications focused on cardiovascular pharmacology and calcium channel modulation.
Product Information
Catalog NumB11945
FormulaC27H24D5N3O6
Molecular Weight496.57
CAS Number2771469-19-1
SMILESCC1=C([C@@H](C2=CC([N+]([O-])=O)=CC=C2)C(C(OC)=O)=C(N1)C)C(O[C@@H]3CN(CC3)CC4=C(C([2H])=C(C([2H])=C4[2H])[2H])[2H])=O
SynonymsMepirodipine-d5; YM-09730-5-d5 Free base
Useful Calculator

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