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Usp14 inhibitor

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Catalog No. A13209

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
IU1 25mg A13209-25
IU1 50mg A13209-50
IU1 100mg A13209-100
IU1 10mM * 1mL in DMSO A13209-10mM-D

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

IU1 is a selective inhibitor of Usp14. It inhibits the catalytic activity of proteasome-associated Usp14 in vitro (IC50 < 4 uM).


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Chemical Information

Catalog Num A13209
Actions Inhibitor
M. Wt 300.37
Formula C18H21FN2O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 314245-33-5
Synonyms IU-1
Chemical Name 1-[1-(4-Fluoro-phenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-pyrrolidin-1-yl-ethanone

Biological Activity

IU1 is a selective inhibitor of Usp14. It inhibits the catalytic activity of proteasome-associated Usp14 in vitro (IC50 < 4 uM).
4.7 μM


Solubility (25°C)* In vitro DMSO 60 mg/mL (199.75 mM)
Water <1 mg/mL (<1 mM)
Ethanol 60 mg/mL (199.75 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 33.29 mL 166.46 mL 332.92mL
0.5 mM 6.66 mL 33.29 mL 66.58 mL
1 mM 3.33 mL 16.65 mL 33.29 mL
5 mM 0.67 mL 3.33 mL 6.66 mL

*The above data is based on the productmolecular weight 300.37. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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