Catalog No.: A13209

Usp14 inhibitor


IU1 Chemical Structure

CAS NO. 314245-33-5

IU1 is a selective inhibitor of Usp14. It inhibits the catalytic activity of proteasome-associated Usp14 in vitro (IC50 < 4 uM).

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25 mg

Regular Price: $100.00

Special Price $80.00

50 mg

Regular Price: $180.00

Special Price $144.00

100 mg

Regular Price: $300.00

Special Price $240.00

10mM * 1mL in DMSO

Regular Price: $71.00

Special Price $56.80

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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Anurag Rathore, .et al. CRISPR-based gene knockout screens reveal deubiquitinases involved in HIV-1 latency in two Jurkat cell models, Sci Rep, 2020, 10: 5350 PMID: 32210344

Biological Activity

IU1 is a selective inhibitor of Usp14. It inhibits the catalytic activity of proteasome-associated Usp14 in vitro (IC50 < 4 uM).
4.7 μM
In vitro (25°C) DMSO 51 mg/mL (169.79 mM)
Water Insoluble
Ethanol 51 mg/mL (169.79 mM)
In vivo 2% DMSO+30% PEG 300+2% Tween 80+ddH2O 4 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 33.29 mL 166.46 mL 332.92 mL
0.5 mM 6.66 mL 33.29 mL 66.58 mL
1 mM 3.33 mL 16.65 mL 33.29 mL
5 mM 0.67 mL 3.33 mL 6.66 mL

*The above data is based on the productmolecular weight 300.37. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13209
Actions Inhibitor
CAS No. 314245-33-5
Formula C18H21FN2O
M. Wt 300.37
Purity >98%
Synonyms IU-1

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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