JAK-IN-1

Catalog No.: A21237

JAK1/2/3 inhibitor

JAK-IN-1

JAK-IN-1 Chemical Structure

CAS NO. 1334673-53-8

JAK-IN-1 is a JAK1/2/3 inhibitor with IC50s of 0.26, 0.8 and 3.2 nM, respectively. JAK-IN-1 shows improved selectivity for JAK3 over JAK1.

Availability: In stock

Package Price Qty
1 mg
$320.00
5 mg
$960.00
10 mg
$1,600.00
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Biological Activity

JAK-IN-1 is a JAK1/2/3 inhibitor with IC50s of 0.26, 0.8 and 3.2 nM, respectively. JAK-IN-1 shows improved selectivity for JAK3 over JAK1.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.29 mL 131.43 mL 262.85 mL
0.5 mM 5.26 mL 26.29 mL 52.57 mL
1 mM 2.63 mL 13.14 mL 26.29 mL
5 mM 0.53 mL 2.63 mL 5.26 mL

*The above data is based on the productmolecular weight 380.44. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21237
Actions Inhibitor
M. Wt 380.44
Formula C20H24N6O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1334673-53-8
SMILES O=C(C1=CNC2=NC=C(C3CC3)N=C21)N[[email protected]@H](C(N4CC(C#N)C4)=O)C(C)(C)C

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