JAK-IN-14 is a selective inhibitor of Janus kinase 1 (JAK1), exhibiting an IC50 of less than 5 μM. This compound demonstrates over eightfold selectivity for JAK1 compared to JAK2 and JAK3. JAK-IN-14 is valuable for research applications focused on elucidating the role of JAK1 in various inflammatory and autoimmune conditions.
JAK-IN-14 is a selective inhibitor of Janus kinase 1 (JAK1), exhibiting an IC50 of less than 5 μM. This compound demonstrates over eightfold selectivity for JAK1 compared to JAK2 and JAK3. JAK-IN-14 is valuable for research applications focused on elucidating the role of JAK1 in various inflammatory and autoimmune conditions.
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