JAK-IN-14

Catalog No.: A33307
JAK1 Inhibitor
JAK-IN-14 is a selective inhibitor of Janus kinase 1 (JAK1), exhibiting an IC50 of less than 5 μM. This compound demonstrates over eightfold selectivity for JAK1 compared to JAK2 and JAK3. JAK-IN-14 is valuable for research applications focused on elucidating the role of JAK1 in various inflammatory and autoimmune conditions.
Grouped product items
Size Price Stock Qty
1mg
$60.00
In stock
5mg
$155.00
In stock
10mg
$250.00
In stock
25mg
$520.00
In stock
50mg
$810.00
In stock
100mg
$1,255.00
In stock
200mg
$1,630.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionJAK-IN-14 is a selective inhibitor of Janus kinase 1 (JAK1), exhibiting an IC50 of less than 5 μM. This compound demonstrates over eightfold selectivity for JAK1 compared to JAK2 and JAK3. JAK-IN-14 is valuable for research applications focused on elucidating the role of JAK1 in various inflammatory and autoimmune conditions.
Product Information
Catalog NumA33307
FormulaC19H15FN4O
Molecular Weight334.35
CAS Number1973485-06-1
SMILESN#CCC1=CC(F)=C(C2=CC=CC3=NC(NC(C4CC4)=O)=CN32)C=C1
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