JAK-IN-30 is a potent and water-soluble inhibitor of Janus kinases (JAKs), exhibiting IC50 values of 2 nM for JAK2, 15 nM for JAK1, 18 nM for JAK3, and 2 nM for TYK2. This compound demonstrates significant biological activity in modulating JAK signaling pathways, making it a valuable tool for investigating inflammatory conditions. Its applicability in research extends to the study of dry eye disease (DED) and other JAK-related disorders.
JAK-IN-30 is a potent and water-soluble inhibitor of Janus kinases (JAKs), exhibiting IC50 values of 2 nM for JAK2, 15 nM for JAK1, 18 nM for JAK3, and 2 nM for TYK2. This compound demonstrates significant biological activity in modulating JAK signaling pathways, making it a valuable tool for investigating inflammatory conditions. Its applicability in research extends to the study of dry eye disease (DED) and other JAK-related disorders.
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