JAK1/2-IN-1 is a selective inhibitor of Janus Kinase 1 (JAK1) and Janus Kinase 2 (JAK2), exhibiting IC50 values of 0.4 nM and 8.1 nM, respectively. In addition to its action on JAK1 and JAK2, it also demonstrates inhibitory effects on interleukin-4 (IL-4) and interleukin-13 (IL-13) with IC50 values of 136.5 nM and 19.1 nM, respectively. This compound is valuable for research applications focused on cytokine signaling and its role in inflammatory diseases.
JAK1/2-IN-1 is a selective inhibitor of Janus Kinase 1 (JAK1) and Janus Kinase 2 (JAK2), exhibiting IC50 values of 0.4 nM and 8.1 nM, respectively. In addition to its action on JAK1 and JAK2, it also demonstrates inhibitory effects on interleukin-4 (IL-4) and interleukin-13 (IL-13) with IC50 values of 136.5 nM and 19.1 nM, respectively. This compound is valuable for research applications focused on cytokine signaling and its role in inflammatory diseases.
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