JAK1-IN-9 is a potent and selective inhibitor of Janus kinase 1 (JAK1), with an IC50 of 72 nM. This compound demonstrates notable selectivity over other JAK family members, exhibiting an inhibition of 12-fold or more. JAK1-IN-9 is valuable for research applications focused on unraveling the roles of JAK1 in cellular signaling pathways and the development of therapeutic strategies for diseases involving JAK1 dysregulation.
JAK1-IN-9 is a potent and selective inhibitor of Janus kinase 1 (JAK1), with an IC50 of 72 nM. This compound demonstrates notable selectivity over other JAK family members, exhibiting an inhibition of 12-fold or more. JAK1-IN-9 is valuable for research applications focused on unraveling the roles of JAK1 in cellular signaling pathways and the development of therapeutic strategies for diseases involving JAK1 dysregulation.
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