JAK2-IN-9 is a selective JAK2 inhibitor with an IC50 of 5 nM, effectively targeting and inhibiting the phosphorylation of JAK2, as well as downstream signaling proteins STAT3 and STAT5. This compound exhibits metabolic stability and induces apoptosis in targeted cells. JAK2-IN-9 is valuable for research focused on myeloproliferative neoplasms (MPNs) and contributes to elucidating the role of JAK2 signaling in hematological malignancies.
JAK2-IN-9 is a selective JAK2 inhibitor with an IC50 of 5 nM, effectively targeting and inhibiting the phosphorylation of JAK2, as well as downstream signaling proteins STAT3 and STAT5. This compound exhibits metabolic stability and induces apoptosis in targeted cells. JAK2-IN-9 is valuable for research focused on myeloproliferative neoplasms (MPNs) and contributes to elucidating the role of JAK2 signaling in hematological malignancies.
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