JANEX-1 hydrochloride is a selective inhibitor of Janus kinase 3 (JAK3), exhibiting a Ki value of 2.3 μM and an IC50 of 78 μM for JAK3 inhibition. This compound does not inhibit JAK1 or JAK2, making it a valuable tool for studying JAK3-specific signaling pathways. JANEX-1 hydrochloride is suitable for research applications focused on immune responses and hematological disorders where JAK3 plays a critical role.
JANEX-1 hydrochloride is a selective inhibitor of Janus kinase 3 (JAK3), exhibiting a Ki value of 2.3 μM and an IC50 of 78 μM for JAK3 inhibition. This compound does not inhibit JAK1 or JAK2, making it a valuable tool for studying JAK3-specific signaling pathways. JANEX-1 hydrochloride is suitable for research applications focused on immune responses and hematological disorders where JAK3 plays a critical role.
Product Information
Catalog Num
A33352
Formula
C16H16ClN3O3
Molecular Weight
333.77
CAS Number
188829-39-2
SMILES
COC1=CC2=NC=NC(NC3=CC=C(O)C=C3)=C2C=C1OC.[H]Cl
Synonyms
WHI-P131 hydrochloride; Jak3 inhibitor I hydrochloride
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
