JD123 is a selective inhibitor of JNK1, demonstrating ATP-competitive inhibition of p38-γ MAPK. It effectively reduces the activity of JNK1 and the expression of cJun (1-135), while exhibiting no inhibitory effects on ERK1, ERK2, or the other p38 MAPK isoforms (α, β, and δ). JD123 is primarily utilized in research applications focused on cell signaling pathways, apoptosis, and inflammatory responses.
JD123 is a selective inhibitor of JNK1, demonstrating ATP-competitive inhibition of p38-γ MAPK. It effectively reduces the activity of JNK1 and the expression of cJun (1-135), while exhibiting no inhibitory effects on ERK1, ERK2, or the other p38 MAPK isoforms (α, β, and δ). JD123 is primarily utilized in research applications focused on cell signaling pathways, apoptosis, and inflammatory responses.
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