JHU37152 is a potent agonist for Designer Receptors Exclusively Activated by Designer Drugs (DREADDs), specifically targeting the hM3Dq and hM4Di receptors with EC50 values of 5 nM and 0.5 nM, respectively, in HEK-293 cells. This compound demonstrates selective displacement of [3H]Clozapine from DREADD sites without affecting other Clozapine-binding sites in mouse brain tissue. JHU37152 is valuable for research applications involving neural circuit manipulation and the study of neuropharmacology.
JHU37152 is a potent agonist for Designer Receptors Exclusively Activated by Designer Drugs (DREADDs), specifically targeting the hM3Dq and hM4Di receptors with EC50 values of 5 nM and 0.5 nM, respectively, in HEK-293 cells. This compound demonstrates selective displacement of [3H]Clozapine from DREADD sites without affecting other Clozapine-binding sites in mouse brain tissue. JHU37152 is valuable for research applications involving neural circuit manipulation and the study of neuropharmacology.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
