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Biological Activity
JIP-1 (153-163) is a peptide inhibitor of c-Jun N-terminal kinase (JNK), based on residues 153-163 of JNK-interacting protein-1 (JIP-1). Binds to JNK with affinity in the micromolar range and minimally inhibits p38 and ERK.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 7.45 mL | 37.27 mL | 74.54 mL |
| 0.5 mM | 1.49 mL | 7.45 mL | 14.91 mL |
| 1 mM | 0.75 mL | 3.73 mL | 7.45 mL |
| 5 mM | 0.15 mL | 0.75 mL | 1.49 mL |
*The above data is based on the productmolecular weight 1341.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A16041 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 438567-88-5 |
| Formula | C61H104N20O14 |
| M. Wt | 1341.6 |
| Purity | >98% |
| Synonyms | TI-JIP |
| SMILES | CC(C)CC(C(=O)NC(CC1=CC=CC=C1)C(=O)N)NC(=O)C(CC(=O)N)NC(=O)C(CC(C)C)NC(=O)C(C(C)O)NC(=O)C(C(C)O)NC(=O)C2CCCN2C(=O)C(CCCN=C(N)N)NC(=O)C(CCCCN)NC(=O)C3CCCN3C(=O)C(CCCN=C(N)N)N |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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