JTV-519 hemifumarate is a selective blocker of the sarcoplasmic reticulum Ca2+-stimulated ATPase (SERCA), with additional activity as a partial agonist of ryanodine receptors in striated muscle. It exhibits antiarrhythmic and cardioprotective properties, making it a valuable tool for research on cardiac function and rhythm disorders. This compound is useful in studies exploring calcium handling in myocardial cells and its implications for heart disease therapies.
JTV-519 hemifumarate is a selective blocker of the sarcoplasmic reticulum Ca2+-stimulated ATPase (SERCA), with additional activity as a partial agonist of ryanodine receptors in striated muscle. It exhibits antiarrhythmic and cardioprotective properties, making it a valuable tool for research on cardiac function and rhythm disorders. This compound is useful in studies exploring calcium handling in myocardial cells and its implications for heart disease therapies.
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