JTV-519 is a calcium-dependent blocker of sarcoplasmic reticulum Ca2+-stimulated ATPase (SERCA) and serves as a partial agonist of ryanodine receptors in striated muscle. This compound exhibits antiarrhythmic and cardioprotective properties, making it valuable for research into cardiac function and arrhythmia prevention. JTV-519 is utilized in studies investigating the modulation of calcium signaling and its implications for cardiovascular health.
JTV-519 is a calcium-dependent blocker of sarcoplasmic reticulum Ca2+-stimulated ATPase (SERCA) and serves as a partial agonist of ryanodine receptors in striated muscle. This compound exhibits antiarrhythmic and cardioprotective properties, making it valuable for research into cardiac function and arrhythmia prevention. JTV-519 is utilized in studies investigating the modulation of calcium signaling and its implications for cardiovascular health.
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