JW74

Catalog No.: A16219

Wnt inhibitor

JW74

JW74 Chemical Structure

CAS NO. 863405-60-1

JW74 is an efficient and specific inhibitor of the canonical Wnt signaling. JW74 shows a reduction of canonical Wnt signaling in the ST-Luc assay with IC50 values of 790 nM.

Availability: In stock

Package Price Qty
5 mg
$70.00
10 mg
$100.00
50 mg
$350.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

JW74 is an efficient and specific inhibitor of the canonical Wnt signaling. JW74 shows a reduction of canonical Wnt signaling in the ST-Luc assay with IC50 values of 790 nM.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.9 mL 109.52 mL 219.05 mL
0.5 mM 4.38 mL 21.9 mL 43.81 mL
1 mM 2.19 mL 10.95 mL 21.9 mL
5 mM 0.44 mL 2.19 mL 4.38 mL

*The above data is based on the productmolecular weight 456.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A16219
Actions Inhibitor
M. Wt 456.52
Formula C24H20N6O2S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 863405-60-1
Synonyms JW-74, JW 74
SMILES CC1=CC=C(C2=NOC(CSC3=NN=C(C4=CC=NC=C4)N3C5=CC=C(OC)C=C5)=N2)C=C1

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