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Keap1-Nrf2-IN-16

Catalog No.: A79521
Bioactive Peptide
Keap1-Nrf2-IN-16 is a bioactive peptide that targets the KEAP1 protein to disrupt its interaction with the Nrf2 transcription factor. This inhibition leads to the stabilization and activation of Nrf2, promoting the expression of antioxidant response elements and enhancing cellular defense mechanisms. Keap1-Nrf2-IN-16 is utilized in research applications related to oxidative stress, cellular protection, and neurodegenerative diseases.
Keap1-Nrf2-IN-16 1362661-40-2 Bioactive Peptide
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionKeap1-Nrf2-IN-16 is a bioactive peptide that targets the KEAP1 protein to disrupt its interaction with the Nrf2 transcription factor. This inhibition leads to the stabilization and activation of Nrf2, promoting the expression of antioxidant response elements and enhancing cellular defense mechanisms. Keap1-Nrf2-IN-16 is utilized in research applications related to oxidative stress, cellular protection, and neurodegenerative diseases.
Product Information
Catalog NumA79521
FormulaC73H114N16O26
Molecular Weight1631.78
CAS Number1362661-40-2
SequenceLeu-Gln-Leu-Asp-Glu-Glu-Thr-Gly-Glu-Phe-Leu-Pro-Ile-Gln
Sequence shorteningLQLDEETGEFLPIQ
SMILESC([C@@H](NC([C@H](CC1=CC=CC=C1)NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC(C)C)N)=O)CCC(N)=O)=O)CC(C)C)=O)CC(O)=O)=O)CCC(O)=O)=O)CCC(O)=O)=O)[C@@H](C)O)=O)=O)CCC(O)=O)=O)=O)CC(C)C)(=O)N2[C@H](C(N[C@H](C(N[C@@H](CCC(N)=O)C(O)=O)=O)[C@H](CC)C)=O)CCC2
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Immunology & Inflammation > Keap1-Nrf2
Peptides