Kenpaullone

Catalog No.: A11220

CDK inhibitor

Kenpaullone Chemical Structure

CAS NO. 142273-20-9

Kenpaullone is a potent inhibitor of CDK1/cyclin B (IC₅₀ = 400 nM), CDK2/cyclin A (IC₅₀ = 680nM) , CDK5 (IC₅₀ = 850nM) and with much less effect other kinases.

Availability: In stock Shipped in 7-10 Days

Package Price Qty
10 mg

Regular Price: $90.00

Special Price $72.00

50 mg

Regular Price: $380.00

Special Price $304.00

100 mg

Regular Price: $650.00

Special Price $520.00

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Kenpaullone is a potent inhibitor of CDK1/cyclin B (IC₅₀ = 400 nM), CDK2/cyclin A (IC₅₀ = 680nM) , CDK5 (IC₅₀ = 850nM) and with much less effect other kinases.
Targets
Target Value
GSK-3βIC50: 0.23μM
CDK1/CyclinBIC50: 0.4μM
CDK2/CyclinAIC50: 0.68μM
CDK5/p35IC50: 0.85μM
CDK2/CyclinEIC50: 7.5μM
ERK2IC50: 9μM
c-SrcIC50: 15μM
CaseinKinase2IC50: 20μM
ERK1IC50: 20μM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 30.56 mL 152.81 mL 305.62 mL
0.5 mM 6.11 mL 30.56 mL 61.12 mL
1 mM 3.06 mL 15.28 mL 30.56 mL
5 mM 0.61 mL 3.06 mL 6.11 mL

*The above data is based on the productmolecular weight 327.2. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11220
Actions Inhibitor
M. Wt 327.2
Formula C16H11BrN2O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 142273-20-9
SMILES C1C2=C(C3=CC=CC=C3NC1=O)NC4=C2C=C(C=C4)Br

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