KN-92

Catalog No.: A15137

CaMK-II Inhibitor

KN-92 Chemical Structure

CAS NO. 176708-42-2

KN-92 is an inactive derivative of KN-93. KN-93 is a selective inhibitor of Ca2+/calmodulin-dependent kinase II (CaMKII), competitively blocking CaM binding to the kinase (Ki = 370 nM).

Availability: In stock

Package Price Qty
5 mg
$45.00
10 mg
$60.00
50 mg
$220.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

KN-92 is an inactive derivative of KN-93. KN-93 is a selective inhibitor of Ca2+/calmodulin-dependent kinase II (CaMKII), competitively blocking CaM binding to the kinase (Ki = 370 nM).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.88 mL 109.41 mL 218.83 mL
0.5 mM 4.38 mL 21.88 mL 43.77 mL
1 mM 2.19 mL 10.94 mL 21.88 mL
5 mM 0.44 mL 2.19 mL 4.38 mL

*The above data is based on the productmolecular weight 456.98. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15137
Actions Inhibitor
M. Wt 456.98
Formula C24H25ClN2O3S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 176708-42-2
Synonyms KN 92, KN92
SMILES CN(CC=CC1=CC=C(C=C1)Cl)CC2=CC=CC=C2NS(=O)(=O)C3=CC=C(C=C3)OC

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