KPT276

Catalog No.: A16341
SINE/CRM1 inhibitor
KPT276, analog of KPT-185, is a selective inhibitor of nuclear export (SINE) and CRM1.
Grouped product items
Product Name Price Stock Qty
KPT276 10mg
Special Price $48.00 Regular Price $60.00
In stock
KPT276 25mg
Special Price $96.00 Regular Price $120.00
In stock
KPT276 50mg
Special Price $176.00 Regular Price $220.00
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Biological Activity
Discription KPT276, analog of KPT-185, is a selective inhibitor of nuclear export (SINE) and CRM1.
Product Information
Catalog Num A16341
Formula C16H10F8N4O
Molecular Weight 426.26
CAS Number 1421919-75-6
SMILES C1C(CN1C(=O)C=CN2C=NC(=N2)C3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F)(F)F
Synonyms KPT-276, KPT 276
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 17 mg/mL (39.87 mM)
Water Insoluble
Ethanol Insoluble
In vivo 30% PEG400+0.5% Tween80+5% propylene glycol 4 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.46 mL 117.3 mL 234.6 mL
0.5 mM 4.69 mL 23.46 mL 46.92 mL
1 mM 2.35 mL 11.73 mL 23.46 mL
5 mM 0.47 mL 2.35 mL 4.69 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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