KT-362 free acid is an intracellular calcium antagonist that exhibits antiarrhythmic and vasodilatory properties. It antagonizes norepinephrine-induced vasoconstriction by reducing inositol phospholipid hydrolysis, leading to decreased intracellular calcium mobilization. This reagent is suitable for investigating the mechanisms of contraction and relaxation in vascular smooth muscle, particularly the roles of intracellular calcium dynamics and inositol phospholipid pathways in vascular contraction.
KT-362 free acid is an intracellular calcium antagonist that exhibits antiarrhythmic and vasodilatory properties. It antagonizes norepinephrine-induced vasoconstriction by reducing inositol phospholipid hydrolysis, leading to decreased intracellular calcium mobilization. This reagent is suitable for investigating the mechanisms of contraction and relaxation in vascular smooth muscle, particularly the roles of intracellular calcium dynamics and inositol phospholipid pathways in vascular contraction.
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