L-054522 is an agonist for somatostatin receptor subtype 2, featuring a Kd of 0.01 nM. This compound effectively inhibits growth hormone secretion from rat primary pituitary cells with an IC50 of 0.05 nM, as well as glucagon and insulin release from isolated mouse pancreatic islet cells, exhibiting IC50 values of 0.05 nM and 12 nM, respectively. L-054522 serves as a valuable tool for exploring somatostatin signaling and its impact on endocrine functions in research applications.
L-054522 is an agonist for somatostatin receptor subtype 2, featuring a Kd of 0.01 nM. This compound effectively inhibits growth hormone secretion from rat primary pituitary cells with an IC50 of 0.05 nM, as well as glucagon and insulin release from isolated mouse pancreatic islet cells, exhibiting IC50 values of 0.05 nM and 12 nM, respectively. L-054522 serves as a valuable tool for exploring somatostatin signaling and its impact on endocrine functions in research applications.
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