L-367773

Catalog No.: A62765
Oxytocin Receptor Antagonist
L-367773 is a selective antagonist of the oxytocin receptor, demonstrating Ki values of 26 nM for the rat uterine oxytocin receptor and 61 nM for the human uterine oxytocin receptor. This compound effectively inhibits oxytocin-stimulated uterine contractions, making it a valuable tool for research related to reproductive biology and uterine physiology. Its oral bioactivity further enhances its utility in pharmacological studies.
Grouped product items
Size Price Stock Qty
25mg
$1,275.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionL-367773 is a selective antagonist of the oxytocin receptor, demonstrating Ki values of 26 nM for the rat uterine oxytocin receptor and 61 nM for the human uterine oxytocin receptor. This compound effectively inhibits oxytocin-stimulated uterine contractions, making it a valuable tool for research related to reproductive biology and uterine physiology. Its oral bioactivity further enhances its utility in pharmacological studies.
Product Information
Catalog NumA62765
FormulaC28H38N4O3S
Molecular Weight510.69
CAS Number152140-41-5
SMILESO=C(N[C@@H]1[C@](C2(C)C)(CS(=O)(N3CCC4(CC3)CCC5=C4C=CC=C5)=O)CC[C@]2([H])C1)CC6=CNC=N6
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