L-779976

Catalog No.: A63897
Somatostatin Receptor Agonist
L-779976 is a somatostatin receptor agonist that exhibits notable anxiolytic effects. When administered into the amygdala and septum of rat brains, it has been shown to modulate anxiety-related behaviors through its complex interactions with somatostatin receptors. This compound is instrumental in research applications focusing on anxiety disorders and neuropharmacology, enabling the investigation of somatostatin's role in stress responses and emotional regulation.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionL-779976 is a somatostatin receptor agonist that exhibits notable anxiolytic effects. When administered into the amygdala and septum of rat brains, it has been shown to modulate anxiety-related behaviors through its complex interactions with somatostatin receptors. This compound is instrumental in research applications focusing on anxiety disorders and neuropharmacology, enabling the investigation of somatostatin's role in stress responses and emotional regulation.
Product Information
Catalog NumA63897
FormulaC33H43N7O3
Molecular Weight585.74
CAS Number214770-19-1
SMILESO=C1N(C2CCN(CC2)C(N[C@@H](C(NC[C@H]3C[C@H](CCC3)CN)=O)[C@H](C4=CNC5=CC=CC=C45)C)=O)C6=CC=CC=C6N1
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