L-Azidohomoalanine is a versatile click chemistry reagent designed as an alkyl chain-based linker for PROTAC synthesis. It features an azide functional group enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, L-Azidohomoalanine can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN moieties. Its unique properties make it suitable for research applications involving targeted protein degradation and modular assembly of multifunctional biomolecules.
L-Azidohomoalanine is a versatile click chemistry reagent designed as an alkyl chain-based linker for PROTAC synthesis. It features an azide functional group enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, L-Azidohomoalanine can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN moieties. Its unique properties make it suitable for research applications involving targeted protein degradation and modular assembly of multifunctional biomolecules.
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