L-Guluronic acid

Catalog No.: A74743
Coagulation Factor Xa Inhibitor
L-Guluronic acid is a coagulation Factor Xa inhibitor that retains the inhibitory activity against Factor Xa while serving as a substitute for L-Iduronic acid in anticoagulant pentasaccharides derived from heparin-like substances. Its capacity to modulate coagulation processes makes it valuable in research focused on coagulation disorders, including deep vein thrombosis and pulmonary embolism. This compound facilitates the exploration of therapeutic strategies aimed at managing these significant vascular conditions.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
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Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionL-Guluronic acid is a coagulation Factor Xa inhibitor that retains the inhibitory activity against Factor Xa while serving as a substitute for L-Iduronic acid in anticoagulant pentasaccharides derived from heparin-like substances. Its capacity to modulate coagulation processes makes it valuable in research focused on coagulation disorders, including deep vein thrombosis and pulmonary embolism. This compound facilitates the exploration of therapeutic strategies aimed at managing these significant vascular conditions.
Product Information
Catalog NumA74743
FormulaC6H10O7
Molecular Weight194.14
CAS Number1986-15-8
SMILES[C@H]([C@@H]([C@@H](C=O)O)O)([C@H](C(O)=O)O)O
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