Lamotrigine

Catalog No.: A11873

Lamotrigine

Lamotrigine Chemical Structure

CAS NO. 84057-84-1

Lamotrigine is a novel anticonvulsant drug for inhibition of 5-HT with IC50 of 240 μM and 474 μM in human platelets and rat brain synaptosomes, and also is a sodium channel blocker.

Availability: In stock

Package Price Qty
10 mg
$50.00
25 mg
$90.00
50 mg
$160.00
100 mg
$280.00
10mM * 1mL in DMSO
$72.00
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Biological Activity

Lamotrigine is a novel anticonvulsant drug for inhibition of 5-HT with IC50 of 240 μM and 474 μM in human platelets and rat brain synaptosomes, and also is a sodium channel blocker.
Targets
Sodium channel 5-HT (human platelets) 5-HT (rat brain synaptosomes)
N/A240 μM474 μM
In vitro (25°C) DMSO 10 mg/mL (39.04 mM)
Water <1 mg/mL (<1 mM)
Ethanol 3 mg/mL (11.71 mM)
In vivo 0.5% methylcellulose 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 39.05 mL 195.24 mL 390.49 mL
0.5 mM 7.81 mL 39.05 mL 78.1 mL
1 mM 3.9 mL 19.52 mL 39.05 mL
5 mM 0.78 mL 3.9 mL 7.81 mL

*The above data is based on the productmolecular weight 256.09. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11873
M. Wt 256.09
Formula C9H7Cl2N5
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 84057-84-1
SMILES C1=CC(=C(C(=C1)Cl)Cl)C2=C(N=C(N=N2)N)N

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