Lapatinib (free base)

Catalog No.: A11752

Lapatinib (free base) Chemical Structure

CAS NO. 231277-92-2

Lapatinib is a dual tyrosine kinase inhibitor which interrupts the HER2 growth receptor pathway.

Availability: In stock

Package Price Qty
10 mg

Regular Price: $30.00

Special Price $24.00

25 mg

Regular Price: $40.00

Special Price $32.00

50 mg

Regular Price: $50.00

Special Price $40.00

100 mg

Regular Price: $70.00

Special Price $56.00

10mM * 1mL in DMSO
$50.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Lapatinib is a dual tyrosine kinase inhibitor which interrupts the HER2 growth receptor pathway.
Targets
Target Value
ErbB2IC50: 9.2nM
EGFRIC50: 10.8nM
ErbB4IC50: 367nM
c-SrcIC50: 3.5μM
C-Raf-1IC50: >10μM
MEKIC50: >10μM
ERKIC50: >10μM
c-FmsIC50: >10μM
CDK1IC50: >10μM
CDK2IC50: >10μM
p38IC50: >10μM
Tie-2IC50: >10μM
VEGFR2IC50: >10μM
In vitro (25°C) DMSO 100 mg/mL (172.09 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 15% Captisol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.21 mL 86.04 mL 172.09 mL
0.5 mM 3.44 mL 17.21 mL 34.42 mL
1 mM 1.72 mL 8.6 mL 17.21 mL
5 mM 0.34 mL 1.72 mL 3.44 mL

*The above data is based on the productmolecular weight 581.1 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11752
M. Wt 581.1
Formula C29H26ClFN4O4S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 231277-92-2
SMILES CS(=O)(=O)CCNCC1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl

Product Tags

Product Tags

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
You may also be interested in the following product(s)
Keywords:buy Lapatinib (free base) | Lapatinib (free base) Supplier | purchase Lapatinib (free base) | Lapatinib (free base) cost | Lapatinib (free base) manufacturer | order Lapatinib (free base) | Lapatinib (free base) distributor | buy 231277-92-2| 231277-92-2 Supplier | purchase 231277-92-2 | 231277-92-2 cost | 231277-92-2 manufacturer | order 231277-92-2 | 231277-92-2 distributor
Rewards