Lapatinib (free base)

Lapatinib is a dual tyrosine kinase inhibitor which interrupts the HER2 growth receptor pathway.
Grouped product items
Product Name Price Stock Qty
Lapatinib 10mg
$30.00
In stock
Lapatinib 25mg
$40.00
In stock
Lapatinib 50mg
$50.00
In stock
Lapatinib 100mg
$70.00
In stock
Lapatinib (free base) 10mM * 1mL in DMSO
$50.00
In stock
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Adooq Products cited in reputable paper
Adooq's Lapatinib (free base) has been cited by 8 publications
  • Aya Hasan Alshammari, .et al. , Biochem Pharmacol, 2022, Mar;197:114914 PMID: 35041812
  • Adi Jacob Berger, .et al. , Nat Cancer, 2021, 2, 1055-1070 PMID: 35121883
  • Hamzehlou S, .et al. , Eur J Pharmacol, 2019, Nov 15;863:172705 PMID: 31574259
  • Momeny M, .et al. , Cell Oncol (Dordr), 2019, Apr 25 PMID: 31025257
  • Tzeng SF, .et al. , FASEB J, 2018, Jun 15:fj201800687 PMID: 29906246
  • Fujita KI, .et al. , J Pharm Sci, 2017, Sep;106(9):2632-2641 PMID: 28479358
  • Yuki Kawasaki, .et al. , Sci Rep, 2016, 6: 31502 PMID: 27531070
  • Tetsuya Saita, .et al. , Biol Pharm Bull. , 2015, 38(10):1652-7 PMID: 26424026
  • Biological Activity
    Discription Lapatinib is a dual tyrosine kinase inhibitor which interrupts the HER2 growth receptor pathway.
    Targets
    Target Value
    Product Information
    Catalog Num A11752
    Formula C29H26ClFN4O4S
    Molecular Weight 581.1
    CAS Number 231277-92-2
    SMILES CS(=O)(=O)CCNCC1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 99 mg/mL (170.37 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 2% DMSO+30% PEG 300+5% Tween 80+ddH2O 9 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 17.21 mL 86.04 mL 172.09 mL
    0.5 mM 3.44 mL 17.21 mL 34.42 mL
    1 mM 1.72 mL 8.6 mL 17.21 mL
    5 mM 0.34 mL 1.72 mL 3.44 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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