Laprituximab emtansine targets the epidermal growth factor receptor (EGFR) as an antibody-drug conjugate (ADC) incorporating the J2898A antibody linked to DM1, an anti-microtubule agent, via the SMCC thioether linker. This compound exhibits potent anti-cancer activity by delivering cytotoxic agents directly to HER1-expressing cells, thereby enhancing therapeutic efficacy while minimizing systemic toxicity. It is suitable for applications in cancer research, particularly in the study of targeted therapies and EGFR-related pathways.
Laprituximab emtansine targets the epidermal growth factor receptor (EGFR) as an antibody-drug conjugate (ADC) incorporating the J2898A antibody linked to DM1, an anti-microtubule agent, via the SMCC thioether linker. This compound exhibits potent anti-cancer activity by delivering cytotoxic agents directly to HER1-expressing cells, thereby enhancing therapeutic efficacy while minimizing systemic toxicity. It is suitable for applications in cancer research, particularly in the study of targeted therapies and EGFR-related pathways.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
