Latanoprost ethyl amide is a modified prostaglandin analog that serves as a selective ocular hypotensive agent. By altering the C-1 carboxyl group to an N-ethyl amide, this compound may offer an alternative delivery mechanism for prostaglandin activity. Recent studies reveal that Latanoprost ethyl amide can be converted to its active free acid form in bovine and human corneal tissue, albeit at a slower rate compared to traditional prostaglandin esters. This unique pharmacokinetic profile may enhance its therapeutic potential in the treatment of intraocular pressure-related conditions.
Latanoprost ethyl amide is a modified prostaglandin analog that serves as a selective ocular hypotensive agent. By altering the C-1 carboxyl group to an N-ethyl amide, this compound may offer an alternative delivery mechanism for prostaglandin activity. Recent studies reveal that Latanoprost ethyl amide can be converted to its active free acid form in bovine and human corneal tissue, albeit at a slower rate compared to traditional prostaglandin esters. This unique pharmacokinetic profile may enhance its therapeutic potential in the treatment of intraocular pressure-related conditions.
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