Catalog No.: A14020

FTase inhibitor


LB42708 Chemical Structure

CAS NO. 226929-39-1

LB42708 is a potent, orally active and selective nonpeptidic farnesyltransferase inhibitor (FTase inhibitor).

Availability: In stock

Package Price Qty
5 mg
10 mg
25 mg
10mM * 1mL in DMSO
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Biological Activity

LB42708 is a potent, orally active and selective nonpeptidic farnesyltransferase inhibitor (FTase inhibitor).
FTase (H-ras) FTase (N-ras) FTase (K-Ras)
0.8 nM1.2 nM2.0 nM
In vitro DMSO 95 mg/mL (171.03 mM)
Water Insoluble
Ethanol Warmed: 82 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18 mL 90.02 mL 180.03 mL
0.5 mM 3.6 mL 18 mL 36.01 mL
1 mM 1.8 mL 9 mL 18 mL
5 mM 0.36 mL 1.8 mL 3.6 mL

*The above data is based on the productmolecular weight 555.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14020
Actions Inhibitor
CAS No. 226929-39-1
Formula C30H27BrN4O2
M. Wt 555.46
Purity >98%
Synonyms LB-42708, LB 42708

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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