LDN-212854

Catalog No.: A12821

BMP receptor inhibitor

LDN-212854

LDN-212854 Chemical Structure

CAS NO. 1432597-26-6

LDN-212854 is an ALK2-Biased BMP Type I Receptor Kinase Inhibitor.

Availability: In stock

Package Price Qty
5 mg
$80.00
10 mg
$140.00
25 mg
$280.00
50 mg
$500.00
10mM * 1mL in DMSO
$124.00
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Biological Activity

LDN-212854 is an ALK2-Biased BMP Type I Receptor Kinase Inhibitor.
Targets
ALK2 ALK1 ALK3 ALK4 ALK5
1.3 nM2.4 nM85.8 nM2133 nM9276 nM
In vitro DMSO 81 mg/mL heating (199.27 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.6 mL 123 mL 246 mL
0.5 mM 4.92 mL 24.6 mL 49.2 mL
1 mM 2.46 mL 12.3 mL 24.6 mL
5 mM 0.49 mL 2.46 mL 4.92 mL

*The above data is based on the productmolecular weight 406.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12821
Actions Inhibitor
M. Wt 406.5
Formula C25H22N6
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1432597-26-6
Synonyms LDN212854, LDN 212854
SMILES C12=C(C3=C4N=CC(C5=CC=C(N6CCNCC6)C=C5)=CN4N=C3)C=CC=C1N=CC=C2

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