Catalog No.: A12715

UCH-L1 Inhibitor


LDN-57444 Chemical Structure

CAS NO. 668467-91-2

LDN-57444 is a potent, reversible, competitive and active site-directed inhibitor of UCHL1.

Availability: In stock

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10 mg
25 mg
50 mg
100 mg
10mM * 1mL in DMSO
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Biological Activity

LDN-57444 is a potent, reversible, competitive and active site-directed inhibitor of UCHL1.
0.4 μM(Ki)0.88 μM25 μM
In vitro (25°C) DMSO 11 mg/mL (27.66 mM)
Water Insoluble
Ethanol Insoluble
In vivo 5% DMSO+corn oil 5 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.15 mL 125.74 mL 251.48 mL
0.5 mM 5.03 mL 25.15 mL 50.3 mL
1 mM 2.51 mL 12.57 mL 25.15 mL
5 mM 0.5 mL 2.51 mL 5.03 mL

*The above data is based on the productmolecular weight 397.64. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12715
Actions Inhibitor
CAS No. 668467-91-2
Formula C17H11Cl3N2O3
M. Wt 397.64
Solubility DMSO
Purity >98%
Synonyms C30, LDN 57444, LDN57444
SMILES CC(=O)O/N=C/1\C2=C(C=CC(=C2)Cl)N(C1=O)CC3=C(C=CC(=C3)Cl)Cl

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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