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Ledipasvir-d6

Catalog No.: A51153
Stable Isotope
Ledipasvir-d6 is a deuterated form of Ledipasvir, an effective inhibitor of the hepatitis C virus NS5A, exhibiting EC50 values of 34 pM against genotype 1a and 4 pM against genotype 1b replicons. Additionally, Ledipasvir serves as a SARS-CoV 3CLpro inhibitor, with an IC50 of 1.62 μM. This stable isotope is suitable for advanced research applications in virology and drug development, particularly in studies involving metabolic tracing and pharmacokinetics.
Ledipasvir-d6 2050041-12-6 Stable Isotope
Grouped product items
Size Price Stock Qty
1mg
$225.00
In stock
5mg
$655.00
In stock
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Research use only. We do not sell to patients.
Data Sheet SDS Compound Handling Instructions

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionLedipasvir-d6 is a deuterated form of Ledipasvir, an effective inhibitor of the hepatitis C virus NS5A, exhibiting EC50 values of 34 pM against genotype 1a and 4 pM against genotype 1b replicons. Additionally, Ledipasvir serves as a SARS-CoV 3CLpro inhibitor, with an IC50 of 1.62 μM. This stable isotope is suitable for advanced research applications in virology and drug development, particularly in studies involving metabolic tracing and pharmacokinetics.
Product Information
Catalog NumA51153
FormulaC49H48D6F2N8O6
Molecular Weight895.04
CAS Number2050041-12-6
SMILESO=C(OC([2H])([2H])[2H])N[C@H](C(N([C@H](C1=NC=C(C2=CC(C(F)(F)C3=C4C=CC(C5=CC=C6N=C([C@H]7N(C([C@@H](NC(OC([2H])([2H])[2H])=O)C(C)C)=O)[C@]8([H])CC[C@@]7([H])C8)NC6=C5)=C3)=C4C=C2)N1)C9)CC%109CC%10)=O)C(C)C
SynonymsGS-5885-d6
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Isotope-Labeled Compounds