Lenalidomide-acetylene-C5-COOH serves as a ligand-linker conjugate targeting the E3 ligase Cereblon (CRBN). This compound facilitates the recruitment of CRBN and can be utilized to synthesize proteolysis-targeting chimeras (PROTACs) by conjugating to protein ligands through a linker. As a click chemistry reagent featuring an alkyne group, Lenalidomide-acetylene-C5-COOH is designed for copper-catalyzed azide-alkyne cycloaddition (CuAAc), enabling the efficient coupling with azide-containing molecules. This product is applicable in studies related to targeted protein degradation and novel therapeutic approaches in cancer research.
Lenalidomide-acetylene-C5-COOH serves as a ligand-linker conjugate targeting the E3 ligase Cereblon (CRBN). This compound facilitates the recruitment of CRBN and can be utilized to synthesize proteolysis-targeting chimeras (PROTACs) by conjugating to protein ligands through a linker. As a click chemistry reagent featuring an alkyne group, Lenalidomide-acetylene-C5-COOH is designed for copper-catalyzed azide-alkyne cycloaddition (CuAAc), enabling the efficient coupling with azide-containing molecules. This product is applicable in studies related to targeted protein degradation and novel therapeutic approaches in cancer research.
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