Leukotriene B5 (LTB5) is a leukotriene receptor activator, primarily influencing inflammatory responses. As a metabolite of eicosapentaenoic acid produced via the 5-lipoxygenase (5-LO) pathway, LTB5 is known to increase the contraction of bullfrog lung strips in a concentration-dependent manner. In vivo studies demonstrate that LTB5 (100 nM) can significantly reduce tumor volume in mice with Tm1 murine melanoma cells. Additionally, LTB5 induces chemokinesis and lysosomal enzyme release from polymorphonuclear leukocytes at significantly lower levels compared to LTB4, and exhibits reduced platelet aggregation.
Leukotriene B5 (LTB5) is a leukotriene receptor activator, primarily influencing inflammatory responses. As a metabolite of eicosapentaenoic acid produced via the 5-lipoxygenase (5-LO) pathway, LTB5 is known to increase the contraction of bullfrog lung strips in a concentration-dependent manner. In vivo studies demonstrate that LTB5 (100 nM) can significantly reduce tumor volume in mice with Tm1 murine melanoma cells. Additionally, LTB5 induces chemokinesis and lysosomal enzyme release from polymorphonuclear leukocytes at significantly lower levels compared to LTB4, and exhibits reduced platelet aggregation.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
