Levetiracetam-d3 is a deuterated form of Levetiracetam, primarily targeting the synaptic vesicle protein SV2A. This antiepileptic compound enhances the efficacy of Temozolomide by promoting apoptosis and inhibiting the proliferation of glioblastoma stem cells. Levetiracetam-d3 also modulates histone deacetylase (HDAC) levels, leading to the silencing of MGMT and thereby increasing the sensitivity of cancer cells to Temozolomide treatment. This reagent is valuable for chemical research applications related to cancer therapy and neuropharmacology.
Levetiracetam-d3 is a deuterated form of Levetiracetam, primarily targeting the synaptic vesicle protein SV2A. This antiepileptic compound enhances the efficacy of Temozolomide by promoting apoptosis and inhibiting the proliferation of glioblastoma stem cells. Levetiracetam-d3 also modulates histone deacetylase (HDAC) levels, leading to the silencing of MGMT and thereby increasing the sensitivity of cancer cells to Temozolomide treatment. This reagent is valuable for chemical research applications related to cancer therapy and neuropharmacology.
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