Levetiracetam is an antiepileptic agent that targets the synaptic vesicle protein SV2A. It has been shown to enhance the effects of Temozolomide on glioblastoma stem cell proliferation and apoptosis. Additionally, Levetiracetam modulates histone deacetylase (HDAC) levels, leading to the silencing of MGMT, which further improves the efficacy of Temozolomide. This compound serves as a valuable chemosensitizer in cancer research applications.
Levetiracetam is an antiepileptic agent that targets the synaptic vesicle protein SV2A. It has been shown to enhance the effects of Temozolomide on glioblastoma stem cell proliferation and apoptosis. Additionally, Levetiracetam modulates histone deacetylase (HDAC) levels, leading to the silencing of MGMT, which further improves the efficacy of Temozolomide. This compound serves as a valuable chemosensitizer in cancer research applications.
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