Catalog No.: A13834

Guanylate cyclase C agonist


Linaclotide Chemical Structure

CAS NO. 851199-59-2

Linaclotide is a peptide agonist of the guanylate cyclase 2C.

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Biological Activity

Linaclotide is a peptide agonist of the guanylate cyclase 2C.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 6.55 mL 32.75 mL 65.5 mL
0.5 mM 1.31 mL 6.55 mL 13.1 mL
1 mM 0.65 mL 3.27 mL 6.55 mL
5 mM 0.13 mL 0.65 mL 1.31 mL

*The above data is based on the productmolecular weight 1526.7531. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13834
Actions Agonist
CAS No. 851199-59-2
Formula C59H79N15O21S6
M. Wt 1526.7531
Purity >98%
SMILES C[[email protected]]1C(=O)N[[email protected]]2CSSC[[email protected]]3C(=O)N[[email protected]](C(=O)N[[email protected]](C(=O)N[[email protected]@H](CSSC[[email protected]](NC(=O)CNC(=O)[[email protected]@H](NC2=O)[[email protected]@H](C)O)C(=O)N[[email protected]@H](CC4=CC=C(C=C4)O)C(=O)O)C(=O)N[[email protected]@H](CSSC[[email protected]@H](C(=O)N3)N)C(=O)N[[email protected]](C(=O)N5CCC[[email protected]]5C(=O)N1)CC(=O)N)CC6=CC=C(C=C6)O)CCC(=O)O

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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