Guanylate Cyclase

16 Items

per page
Set Descending Direction
Catalog No.
Product Name
Product Information
Product Citation
  1. sGC stimulator

    Riociguat (BAY 63-2521; BAY 632521) is a stimulator of soluble guanylate cyclase (sGC).
  2. sGC activator

    YC-1 is a direct activator of soluble Guanylyl Cyclase (sGC), independent of Nitric Oxide.
  3. guanylate cyclase activator

    (4-Acetamidocyclohexyl) nitrate (BM121307) is a guanylate cyclase activator that was in phase I development for the treatment of ischaemic heart disorders. The research has been discontinued.
  4. guanylate cyclase (sGC) stimulator

    Olinciguat (IW-1701) is an oral guanylate cyclase (sGC) stimulator with concentration-dependent stimulation of sGC in purified rat and human enzyme assays and a whole cell assay.
  5. Guanylate cyclase C agonist

    Linaclotide is a peptide agonist of the guanylate cyclase 2C.
  6. sGC activator?€?

    BAY 41-2272 is a direct and NO-independent soluble guanylate cyclase (sGC) stimulator.
  7. guanylate cyclase stimulator

    Praliciguat (IW-1973) is a potent and orally active soluble guanylate cyclase stimulator, enhances NO signaling, acts as a vasodilator. Praliciguat (IW-1973) stimulates sGC in HEK-293 cells with an EC50 of 197 nM.
  8. soluble guanylate cyclase stimulator

    Runcaciguat is an orally active stimulator of soluble guanylate cyclase, and is used in the research of cardiovascular and renal diseases combined with selective partial adenosine A1 receptor agonists.
  9. guanylate cyclase stimulator

    Nelociguat (BAY60-4552) is a nitric oxide sensitive soluble guanylate cyclase stimulator.
  10. guanylate cyclase stimulator

    Vericiguat (BAY1021189) is a potent, orally available and soluble guanylate cyclase stimulator.
  11. sGC activator

    Cinaciguat is an activator of guanylate cyclase (sGC), and used for acute decompensated heart failure.
  12. GC-C receptor agonist

    Plecanatide acetate is a guanylate cyclase-C (GC-C) receptor agonist, with an EC50 of 190 nM in T84 cells. Plecanatide acetate shows anti-inflammatory activity in models of murine colitis.
  13. sGC inhibitor

    NS-2028 is a highly selective soluble Guanylyl Cyclase (sGC) inhibitor with IC50 values of 30 nM and 200 nM for basal and NO-stimulated enzyme activity.
  14. guanylate cyclase (GC) activator

    Cinaciguat hydrochloride is a potent soluble guanylate cyclase (GC) activator with EC50 of 15 nM in platelets.
  15. soluble guanylyl cyclase inhibitor

    ODQ is a potent and selective soluble guanylyl cyclase (sGC, nitric oxide-activated enzyme) inhibitor. ODQ enhances the pro-apoptotic effects of Cisplatin in human mesothelioma cells.
  16. MM 419447, a linaclotide metabolite, is a guanylate cyclase-C agonist. MM 419447 has the potential for the research of the irritable bowel syndrome with constipation (IBS-C).

16 Items

per page
Set Descending Direction