Catalog No.
Product Name
Application
Product Information
Product Citation
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sGC stimulator
Riociguat (BAY 63-2521; BAY 632521) is a stimulator of soluble guanylate cyclase (sGC). -
sGC activator
YC-1 is a direct activator of soluble Guanylyl Cyclase (sGC), independent of Nitric Oxide. -
guanylate cyclase activator
(4-Acetamidocyclohexyl) nitrate (BM121307) is a guanylate cyclase activator that was in phase I development for the treatment of ischaemic heart disorders. The research has been discontinued. -
guanylate cyclase (sGC) stimulator
Olinciguat (IW-1701) is an oral guanylate cyclase (sGC) stimulator with concentration-dependent stimulation of sGC in purified rat and human enzyme assays and a whole cell assay. -
Guanylate cyclase C agonist
Linaclotide is a peptide agonist of the guanylate cyclase 2C. -
sGC activator?€?
BAY 41-2272 is a direct and NO-independent soluble guanylate cyclase (sGC) stimulator. -
guanylate cyclase stimulator
Praliciguat (IW-1973) is a potent and orally active soluble guanylate cyclase stimulator, enhances NO signaling, acts as a vasodilator. Praliciguat (IW-1973) stimulates sGC in HEK-293 cells with an EC50 of 197 nM. -
soluble guanylate cyclase stimulator
Runcaciguat is an orally active stimulator of soluble guanylate cyclase, and is used in the research of cardiovascular and renal diseases combined with selective partial adenosine A1 receptor agonists. -
guanylate cyclase stimulator
Nelociguat (BAY60-4552) is a nitric oxide sensitive soluble guanylate cyclase stimulator. -
guanylate cyclase stimulator
Vericiguat (BAY1021189) is a potent, orally available and soluble guanylate cyclase stimulator. -
sGC activator
Cinaciguat is an activator of guanylate cyclase (sGC), and used for acute decompensated heart failure. -
GC-C receptor agonist
Plecanatide acetate is a guanylate cyclase-C (GC-C) receptor agonist, with an EC50 of 190 nM in T84 cells. Plecanatide acetate shows anti-inflammatory activity in models of murine colitis. -
guanylate cyclase (GC) activator
Cinaciguat hydrochloride is a potent soluble guanylate cyclase (GC) activator with EC50 of 15 nM in platelets.
