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Linezolid (PNU-100766)

Catalog No.: A10533

Protein synthesis inhibitor

Linezolid (PNU-100766)

Linezolid (PNU-100766) Chemical Structure

CAS NO. 165800-03-3

Linezolid is a synthetic antibiotic used for the treatment of serious infections.

Availability: In stock

Package Price Qty
10 mg
100 mg
10mM * 1mL in DMSO
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Viktoria Lazar, .et al. Antibiotic combinations reduce Staphylococcus aureus clearance, Nature, 2022, 610: 540-546 PMID: 36198788
  • Zewen Wen, .et al. In vitro activity and adaptation strategies of eravacycline in clinical Enterococcus faecium isolates from China, J Antibiot (Tokyo), 2022, Sep;75(9):498-508 PMID: 35896611
  • Meikle V, .et al. A protein complex from human milk enhances the activity of antibiotics and drugs against Mycobacterium tuberculosis, Antimicrob Agents Chemother, 2018, Nov 12. pii: AAC.01846-18 PMID: 30420480

Biological Activity

Linezolid is a synthetic antibiotic used for the treatment of serious infections.
In vitro (25°C) DMSO 62 mg/mL (183.78 mM)
Water Insoluble
Ethanol 7 mg/mL (20.75 mM)
In vivo 30% PEG400+0.5% Tween80+5% propylene glycol 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 29.65 mL 148.24 mL 296.47 mL
0.5 mM 5.93 mL 29.65 mL 59.29 mL
1 mM 2.96 mL 14.82 mL 29.65 mL
5 mM 0.59 mL 2.96 mL 5.93 mL

*The above data is based on the productmolecular weight 337.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10533
Actions Inhibitor
CAS No. 165800-03-3
Formula C16H20FN3O4
M. Wt 337.3
Purity >98%
Synonyms Zyvox, PNU-100766, U-100766, Zyvoxid, Zyvoxam
SMILES CC(=O)NC[[email protected]]1CN(C(=O)O1)C2=CC(=C(C=C2)N3CCOCC3)F

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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