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- Viktoria Lazar, .et al. Antibiotic combinations reduce Staphylococcus aureus clearance, Nature, 2022, 610: 540-546 PMID: 36198788
- Zewen Wen, .et al. In vitro activity and adaptation strategies of eravacycline in clinical Enterococcus faecium isolates from China, J Antibiot (Tokyo), 2022, Sep;75(9):498-508 PMID: 35896611
- Meikle V, .et al. A protein complex from human milk enhances the activity of antibiotics and drugs against Mycobacterium tuberculosis, Antimicrob Agents Chemother, 2018, Nov 12. pii: AAC.01846-18 PMID: 30420480
Biological Activity
Linezolid is a synthetic antibiotic used for the treatment of serious infections.
| In vitro (25°C) | DMSO | 62 mg/mL (183.78 mM) | |
| Water | Insoluble | ||
| Ethanol | 7 mg/mL (20.75 mM) | ||
| In vivo | 30% PEG400+0.5% Tween80+5% propylene glycol | 28 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 29.65 mL | 148.24 mL | 296.47 mL |
| 0.5 mM | 5.93 mL | 29.65 mL | 59.29 mL |
| 1 mM | 2.96 mL | 14.82 mL | 29.65 mL |
| 5 mM | 0.59 mL | 2.96 mL | 5.93 mL |
*The above data is based on the productmolecular weight 337.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A10533 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 165800-03-3 |
| Formula | C16H20FN3O4 |
| M. Wt | 337.3 |
| Purity | >98% |
| Synonyms | Zyvox, PNU-100766, U-100766, Zyvoxid, Zyvoxam |
| SMILES | CC(=O)NC[[email protected]]1CN(C(=O)O1)C2=CC(=C(C=C2)N3CCOCC3)F |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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